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Docusate for constipation
Medicines in Practice is a series of evidence–based publications specifically designed to support stakeholder medicines optimisation services. The series aims to maximise health gains through the optimum use of medicines, by influencing and changing prescribing behaviour. This document aims to review the evidence base for the use of docusate in the management of constipation, and […]
Pylera for the eradication of Helicobacter Pylori infection
Overview Medicines in Practice is a series of evidence–based publications specifically designed to support stakeholder medicines optimisation services. The series aims to maximise health gains through the optimum use of medicines, by influencing and changing prescribing behaviour. Pylera is a new triple fixed-dose combination capsule containing bismuth, metronidazole and tetracycline. In combination with omeprazole, it […]
Formulary assessment – Budesonide 4mg suppositories
Formulary assessment tools are templates to support local decision making. They list NICE guidance, MHRA safety advice, and other relevant high quality advice and guidelines relevant to making decisions for local formularies. The templates are pre-populated with useful information to reduce duplication of effort, with space for the addition of local information as appropriate. The […]
Oral Sucralfate use in primary care
There have been concerns raised previously about the safety profile and efficacy of sucralfate for long-term use. The withdrawal of ranitidine from the UK marketplace in 2019, and subsequent concerns over the long-term use of proton pump inhibitors (PPIs) in certain patients have brought these concerns back in focus. This document aims to distil the […]
Formulary assessment – Budesonide 9mg MR tablets (Cortiment)
Formulary assessment tools are templates to support local decision making. They list NICE guidance, MHRA safety advice, and other relevant high quality advice and guidelines relevant to making decisions for local formularies. The templates are pre-populated with useful information to reduce duplication of effort, with space for the addition of local information as appropriate. The […]
Budesonide orodispersible tablets for maintenance of remission in eosinophilic oesophagitis
Budesonide orodispersible tablets (Jorveza) are indicated for induction and maintenance of remission in adults with eosinophilic oesophagitis. A NICE technology appraisal recommended budesonide ODT for induction of remission but did not address maintenance. This review assesses the evidence for use in maintenance treatment. Download the full review below to read more.
Gastro-intestinal System
This report looks at prescribing trends in primary care for for the Gastro-intestinal system at CCG and STP level with particular focus on Dyspepsia, Antisecretory drugs, Acute Diarrhoea, Chronic Bowel Disorders and Laxatives. If you have any queries about the content of the report please contact us at nuth.nyrdtc.rxsupp@nhs.net Frequency Bi-annually Data Period April 2018 […]
Long-Term Use Of PPIs – Bulletin
Long-term use of PPIs is not recommended in several indications as it has been linked to adverse effects including hypomagnesaemia, vitamin B12 deficiency, increased fracture risk and increased risk of MI. This bulletin aims to highlight the current national guidance, potential adverse effects associated with long term PPI use and prescribing patterns on a CCG […]
Naldemedine for the treatment of opioid induced constipation
Naldemedine is the second oral peripherally acting μ-opioid receptor antagonist to be launched,after naloxegol. It is licensed for the treatment of opioid induced constipation (OIC) in adults whohave previously been treated with laxatives.