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Safer Medication Use – Propranolol in the treatment of anxiety
Propranolol is increasingly used for the treatment of anxiety. However, several recent critical incidents have raised concerns that there may still be a lack of awareness amongst prescribers over the risks associated with propranolol in overdose. This report aims to raise awareness of the potential toxicity of propranolol in overdose and highlight a specific group […]
Safer Medication Use – Opioids and gabapentinoids
The use of combination opioids and gabapentinoids is associated with an increased risk of adverse events. Gabapentinoid overdose is much more likely to be fatal when combined with opioids and there is a greater risk of gabapentinoid dependence in patients with a history of opioid use disorder. There are limited circumstances when patients should be […]
Safer Medication Use – Ethanol in oral medicines for children
Ethanol is commonly used as an excipient in medicines, which is problematic in several patient groups but particularly so in children. The effects of chronic exposure to even small amounts of alcohol have not been well studied in children. In particular, phenobarbital elixir contains ethanol in such high amounts that children may ingest the equivalent […]